李筠，女，福建福州人，理学博士。现任免疫生物学系副教授，硕士生导师。
学术方向：以肺癌和胃癌为疾病模型，研究肿瘤免疫微环境重塑的调控机制及诊疗策略。迄今发表SCI研究论文18篇，其中第一或通讯作者论文11篇，包括Nature Communications, Cancer Research（2篇），the Journal of Pathology（2篇）等权威期刊。所发表论文累计被引733次，单篇最高被引144次。主持国家自然科学基金2项，广东省自然科学基金面上项目1项，广州市科技计划基础研究计划1项等。兼任暨南大学科学技术协会第一届会员，中华医学会福建省微生物与免疫学分会青年委员。
教育及工作经历
2005.9 - 2009.6 山东大学生命科学学院 学士
2009.9 - 2014.6 中山大学中山医学院 博士
2014.8 - 2016.8 福建医科大学基础医学院 病原生物学系
2016.8 - 至今 暨南大学生命科学技术学院 免疫生物学系
研究论文
代表性论文：
Ting Dai#, Xin Zhang#, Xiang Zhou#, Xiaodi Huang, Xiaoxia Hu, Feiyue Xing, Han Tian*, Yun Li*. LncRNA VAL facilities PKM2 enzymatic activity to promote glycolysis and malignancy of gastric cancer. Clinical and Translational Medicine, 2022, 12(10): e1088.（通讯作者，中科院1区Top，IF=8.554）
Yun Li#,*, Chenying Liu#, Xin Zhang, Xiaodi Huang, Shujun Liang, Feiyue Xing*, Han Tian*. CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/β-catenin signalling pathway. British Journal of Cancer, 2022, 126(12): 1684-1694.（第一/共同通讯作者，中科院1区Top，IF=9.075）
Han Tian#, Rong Lian#, Yun Li#, Chenying Liu, Shujun Liang, Wei Li, Tianyu Tao, Xingui Wu, Yaokai Ye, Xia Yang, Jian Han, Xuwei Chen, Jun Li, Yukai He, Mengfeng Li, Jueheng Wu*, Junchao Cai*. AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation. Nature Communications, 2020, 11(1): 5127.（共同第一作者，中科院1区Top，IF=17.694）
Yun Li#, Liwen Deng#, Xiaohui Zhao#, Bohan Li, Dong Ren, Lihong Yu, Hehai Pan, Qing Gong, Libing Song, Xiang Zhou*, Ting Dai*. Tripartite motif‐containing 37 promotes the aggressiveness of non‐small‐cell lung cancer cells by activating the NF-κB pathway. The Journal of Pathology, 2018, 246(3): 366-378.（第一作者，中科院1区Top，IF=9.883）
Yun Li#, Xiaoli Yan#, Jiajian Shi, Yun He, Jie Xu, Liying Lin, Wannan Chen, Xinjian Lin*, Xu Lin*. Aberrantly expressed miR-188-5p promotes gastric cancer metastasis by activating Wnt/β-catenin signaling. BMC Cancer, 2019, 19(1): 505.（第一作者，中科院2区Top，IF=4.638）
Jianxin Ye#, Jinsheng Huang#, Jie Xu, Qiang Huang, Jinzhou Wang, Wenjing Zhong, Xinjian Lin, Yun Li*, Xu Lin*. ERp29 controls invasion and metastasis of gastric carcinoma by inhibition of epithelial-mesenchymal transition via PI3K/Akt signaling pathway. BMC Cancer, 2017, 17(1): 626.（共同通讯作者，中科院2区Top，IF=4.638）
Ting Dai#, Xiaohui Zhao#, Yun Li#, Lihong Yu, Yanan Li, Xiang Zhou*, Qing Gong*. miR-423 promotes breast cancer invasion by activating NF-κB signaling. OncoTargets and Therapy, 2020, 13: 5467-5478.（共同第一作者，中科院3区，IF=4.345）
Yong Peng, Jiaoying Jia, Zhongzhong Jiang, Dezhi Huang, Yugang Jiang*, Yun Li*. Oncogenic DIRAS3 promotes malignant phenotypes of glioma by activating EGFR-AKT signaling. Biochemical and Biophysical Research Communications, 2018, 505(2): 413-418.（通讯作者，中科院3区，IF=3.322）
Yun Li, Wei Li, Zhe Ying, Han Tian, Xun Zhu, Jun Li, Mengfeng Li*. Metastatic Heterogeneity of Breast Cancer Cells Is Associated with Expression of a Heterogeneous TGF beta-Activating miR424-503 Gene Cluster. Cancer Research, 2014, 74(21): 6107-18.（第一作者，中科院1区Top，IF=13.312）
Zhe Ying#, Yun Li#, Jueheng Wu, Xun Zhu, Yi Yang, Han Tian, Wei Li, Bo Hu, Shi-Yuan Cheng, Mengfeng Li*. Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype. Cancer Research, 2013, 73(2): 990-9.（共同第一作者，中科院1区Top，IF=13.312）
Libing Song#,*, Lan Wang#, Yun Li#, Huaping Xiong, Jueheng Wu, Jun Li, Mengfeng Li*. Sam68 up-regulation correlates with, and its down-regulation inhibits, proliferation and tumourigenicity of breast cancer cells. The Journal of Pathology, 2010, 222(3): 227-37.（共同第一作者，中科院1区Top，IF=9.883）
其他论文：
Zhe Ying#, Han Tian#, Yun Li, Rong Lian, Wei Li, Shanshan Wu, Hui-Zhong Zhang, Jueheng Wu, Lei Liu, Junwei Song, Hongyu Guan, Junchao Cai, Xun Zhu, Jun Li, Mengfeng Li*. CCT6A suppresses SMAD2 and promotes prometastatic TGF-β signaling. The Journal of Clinical Investigation, 2017, 127(5): 1725-1740.（中科院1区Top，IF=19.486）
JiaBin Wang#, ZuWei Wang#, Yun Li, ChaoQun Huang, ChaoHui Zheng, Ping Li, Jian-Wei Xie, Jian-Xian Lin, Jun Lu, Qi-Yue Chen, Long-Long Cao, Mi Lin, Ru-Hong Tu, Yao Lin*, ChangMing Huang*. CDK5RAP3 acts as a tumor suppressor in gastric cancer through inhibition of β-catenin signaling. Cancer Letters, 2017, 385: 188-197.（中科院1区Top，IF=9.756）
Jianxin Ye#, Jie Xu#, Yun Li, Qiang Huang, Jinsheng Huang, Jinzhou Wang, Wenjing Zhong, Xinjian Lin, Wannan Chen*, Xu Lin*. DDAH1 mediates gastric cancer cell invasion and metastasis via Wnt/β‐catenin signaling pathway. Molecular Oncology, 2017, 11(9): 1208-1224.（中科院2区，IF=7.449）
Liping Liu#, Hongyu Guan#, Yun Li, Zhe Ying, Jueheng Wu, Xun Zhu, Libing Song, Jun Li*, Mengfeng Li*. Astrocyte elevated gene 1 interacts with acetyltransferase p300 and c-Jun to promote tumor aggressiveness. Molecular and Cellular Biology, 2017, 37(5): e00456-16.（中科院3区，IF=5.124）
Ping Li*, Xi Lin, JunRong Zhang, Yun Li, Jun Lu, FeiChao Huang, ChaoHui Zheng, JianWei Xie, JiaBin Wang, ChangMing Huang*. The expression of presenilin 1 enhances carcinogenesis and metastasis in gastric cancer. Oncotarget, 2016, 7(9):10650-62.（IF=5.168）
Haiyin Zheng#, Fuxing Zhang#, Xinjian Lin, Changming Huang, Yiqin Zhang, Yun Li, Jianyin Lin, Wannan Chen*, Xu Lin*. MicroRNA-1225-5p inhibits proliferation and metastasis of gastric carcinoma through repressing insulin receptor substrate-1 and activation of beta-catenin signaling. Oncotarget, 2016, 7(4):4647-63.（IF=5.168）
Libing Song#, Liping Liu#, Zhiqiang Wu, Yun Li, Zhe Ying, Chuyong Lin, Jueheng Wu, Bo Hu, Shi-Yuan Cheng, Mengfeng Li, Jun Li*. TGF-beta induces miR-182 to sustain NF-kappa B activation in glioma subsets. The Journal of Clinical Investigation, 2012, 122(10): 3563-78.（中科院1区Top，IF=19.486）
主持科研项目
国家自然科学基金面上项目，TRIM11/IL-33轴驱动非小细胞肺癌溶骨性骨转移的机制研究，82173225，2022.01-2025.12，54.70万元，在研
国家自然科学基金青年科学基金项目，miR-188-5p促进胃癌转移的机制研究，81502125，2016.01-2018.12，19.00万元，已结题
广东省自然科学基金面上项目，TRIM11促进非小细胞肺癌淋巴结转移的机制研究，2022A1515012211，2022.01-2024.12，10.00万元，在研
广州市科技计划基础研究计划，CCT6A调控Wnt/β-catenin信号通路驱动胃癌恶性进展的机制研究，202102020022，2021.04-2023.03，5.00万元，在研
暨南大学科研培育与创新基金跃升计划，长非编码RNA GAPLINC激活TLR信号通路促进胃癌转移的机制研究，21617441，2017.01-2018.12，12.00万元，已结题
暨南大学学科建设优秀青年骨干，2022年度，3.76万元
